Figure 2.

Reference glucose measurements and corresponding implanted CGM trace after IV glucose administration in a swine model. While the direct measurement of glucose using a handheld glucometer indicated an increase in BG, the sensor was unable to accurately track rapid fluctuations in BG. The BG maximum detected by the continuous sensor was thus both delayed in time and attenuated in magnitude. These shortcomings on the part of the sensor are further worsened by foreign body reactions.³⁸