Table 2.

Enriched biological processes of up-regulated and down-regulated transcripts in response to handling stress

GO ID	GO term	p-value	Fold enrichment
	Enrichment of up regulated transcripts in skeletal muscle under stress
GO:0043632	Modification-dependent macromolecule catabolic process	2.3E-06	3.8
GO:0019941	Modification-dependent protein catabolic process	2.3E-06	3.8
GO:0044257	Cellular protein catabolic process	3.6E-06	2.7
GO:0008104	Protein localization	6.8E-06	2.8
GO:0015031	Protein transport	7.4E-06	2.8
GO:0045184	Establishment of protein localization	7.4E-06	3.4
GO:0051603	Proteolysis involved in cellular protein catabolic process	9.1E-06	3.4
GO:0044265	Cellular macromolecule catabolic process	1.2E-05	3.2
GO:0046907	Intracellullar transport	1.4E-05	3.3
GO:0030163	Protein catabolic process	3.0E-05	3.1
GO:0009057	Macromolecule catabolic process	8.4E-05	2.8
GO:0006396	RNA processing	3.3E-04	2.8
GO:0006511	Ubiquitin-dependent protein catabolic process	4.4E-03	3.0
	Enrichment of down regulated transcripts in skeletal muscle under stress
GO:0006941	Striated muscle contraction	1.9E-06	4.3
GO:0007517	Muscle organ development	4.3E-06	4.2
GO:0006936	Muscle contraction	5.5E-06	5,7
GO:0003012	Muscle system process	2.3E-05	3.5
GO:0014706	Striated muscle tissue development	3.1E-05	4.9
GO:0060537	Muscle tissue development	5.8E-05	6.7
GO:0048738	Cardiac muscle tissue development	6.6E-05	6.7
GO:0043462	Regulation of ATPase activity	9.5E-05	3.5
GO:0060048	Cardiac muscle contraction	2.5E-03	4.2
GO:0006937	Regulation of muscle contraction	6.5E-03	3.1