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. 2015 Dec 1;16:400. doi: 10.1186/s12859-015-0827-2

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© Meckbach et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — PC-TraFF significant collaborating TFBS pairs based on promoter sequences of human RefSeq genes. Blue lines denote interactions between TFs whose importance is experimentally verified whereas red lines indicate potential interactions between transcription factors that have not been experimentally validated yet