Table 1.
Anthropometric characteristics and pulmonary function of 60 patients with CF
| Characteristics | CF (n = 60) | Males (n = 35) | Females (n = 25) |
|---|---|---|---|
| Age, yr | 33.5 ± 10.5 | 36.3 ± 11.0* | 29.6 ± 7.6 |
| BMI, Kg/ m2 | 23.1 ± 3.0 | 23.2 ± 2.7 | 23 ± 3.4 |
| FEV1,L | 2.59 ± 0.79 | 2.74 ± 0.88 | 2.37 ± 0.59 |
| FEV1, % predicted | 73.1 ± 19.9 | 68.8 ± 20.9* | 71.9 ± 16.8 |
| FVC, L | 3.80 ± 1.00 | 4.22 ± 1.08* | 3.22 ± 0.54 |
| FVC, %predicted | 90.0 ± 18.0 | 88.0 ± 21.7 | 93.3 ± 12.2 |
| TLC, % predicted | 98.5 ± 18.8 | 93.9 ± 19.8* | 105.0 ± 15.0 |
| DLCO, % predicted | 83.9 ± 15.5 | 84.6 ± 17.1 | 82.9 ± 13.3 |
| Pseudomonas aeruginosa colonization, n (%) | 39 (65) | 24 (68.5) | 15 (60) |
| Staphylococcus aureus colonization, n (%) | 41 (68.3) | 26 (74.2) | 15 (60) |
| Burkholderia cepacia colonization, n (%) | 2 (3.3) | 2 (5.7) | 0 (0) |
| Pancreatic insufficiency, n (%) | 40 (66.6) | 23 (65.7) | 17 (68) |
| CF-related diabetes, n (%) | 14 (23.3) | 8 (22.9) | 6 (24) |
| 508 del homozygous/heterozygous | 14/33 | 6/23* | 8/10 |
| Number of exacerbations/year | 2.38 ± 2.36 | 2.00 ± 1.69 | 2.92 ± 3.00 |
Data are presented as mean ± SD, unless otherwise stated
DL CO diffusion capacity of the lung for carbon monoxide; FVC forced vital capacity; TLC total lung capacity
*P < 0.05, differences between men and women with CF