Table 1.

Clinicopathological factors

Factors	Non-responders	%	Responders	%	P value
	n = 62		n = 64
	Number		Number
Age [mean (SD)]	54.3 (9.1)		57.0 (12.5)		0.713
Sex					0.472
Male	34	54.8	31	48.4
Female	28	45.2	33	51.6
Histology
Adenocarcinoma	All		All
Histological grade					0.485
Well	No		No
Moderately	32	51.6	37	57.8
Poorly	30	48.4	27	42.2
Depth of tumor invasion
ss, se, si	All		All
Lymph node metastasis					0.292
≤3	33	53.2	40	62.5
>3	29	46.8	24	37.5
Venous invasion					0.383
Absent	35	56.5	41	64.1
Present	27	43.5	23	35.9
Nerve invasive					0.001*
Absent	39	62.9	21	32.8
Present	23	37.1	43	67.2
Liver metastasis					0.637
Absent	17	27.4	20	31.3
Present	45	72.6	44	68.7
Lung metastasis					0.248
Absent	50	80.6	46	71.9
Present	12	19.4	18	28.1
Tumor location					0.072
Distal colon	38	61.3	29	45.3
Proximal colon	24	38.7	35	54.7

subserosa (ss), penetration of serosa (se), and invasion of adjacent

structures (si), * P < 0.05