Table 1.
Summary of clinicopathological features of OSCCs and IHC expression patterns of NANOG, CD44, and mutant p53
| NANOG | CD44 | Mutant p53 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Total No. | +++ | ++ | +&– | ++ | + | – | + | – | |
| No. of cases | 57 | 21 | 18 | 18 | 28 | 21 | 8 | 34 | 23 |
| Tumor sites | |||||||||
| Gingiva | 27 | 13 | 8 | 6 | 10 | 11 | 6 | 13 | 14 |
| Cheek | 4 | 0 | 3 | 1 | 2 | 2 | 0 | 3 | 1 |
| Palate | 10 | 4 | 3 | 3 | 9 | 1 | 0 | 10 | 0 |
| Tongue | 9 | 0 | 2 | 7 | 2 | 5 | 2 | 4 | 5 |
| FOM | 7 | 4 | 2 | 1 | 5 | 2 | 0 | 4 | 3 |
| Tumor stage | |||||||||
| I + II | 24 | 6 | 4 | 14 | 10 | 9 | 5 | 11 | 13 |
| III + IV | 33 | 15 | 14 | 4 | 18 | 12 | 3 | 23 | 10 |
| Neck node | |||||||||
| N0 | 34 | 9 | 10 | 15 | 13 | 15 | 6 | 16 | 18 |
| N+ | 23 | 12 | 8 | 3 | 15 | 6 | 2 | 18 | 5 |
| Histo grade | |||||||||
| Well | 22 | 4 | 4 | 14 | 9 | 9 | 4 | 6 | 16 |
| Mod + Poor | 35 | 17 | 14 | 4 | 19 | 12 | 4 | 28 | 7 |
| Antibody | |||||||||
| Dilution rate | 1:250 | 1:100 | 1:200 | ||||||
| Source (Lot No.) | Abcam™ (ab109250) | Abcam™ (ab51037) | Abcam™ (ab32049) | ||||||
Abbreviations: FOM floor of mouth, N0 negative neck node, N+ positive neck node, Well well-differentiated OSCC, Mod + Poor moderately and poorly differentiated OSCC