Table 3.
Number of deaths, cases and case fatality ratio (CFR, %) by age group for the 840 MRU-confirmed cases that did not link to a HES meningococcal disease ICD10 code (MRU+/HESA39-)
| Age group | Linked+/Infection-related | NHS number+/Unlinked | Linked+/Another-pathogen | Linked+/Not-infection | No NHS number | All cases |
|---|---|---|---|---|---|---|
| <1y | 5/50 (10.0 %) | 20/43 (46.5 %) | 0/9 (0.0 %) | 1/2 (50.0 %) | 7/63 (11.1 %) | 33/167 (19.8 %) |
| 1-4y | 0/62 (0.0 %) | 16/33 (48.5 %) | 2/23 (8.7 %) | 0/4 (0.0 %) | 5/77 (6.5 %) | 23/199 (11.6 %) |
| 5-14y | 0/33 (0.0 %) | 5/16 (31.3 %) | 0/5 (0.0 %) | 0/3 (0.0 %) | 2/34 (5.9 %) | 7/91 (7.7 %) |
| 15-24y | 5/25 (20.0 %) | 10/51 (19.6 %) | 1/4 (25.0 %) | 0/2 (0.0 %) | 3/37 (8.1 %) | 19/119 (16.0 %) |
| 25-44y | 1/11 (9.1 %) | 6/25 (24.0 %) | 0/2 (0.0 %) | 0/2 (0.0 %) | 2/37 (5.4 %) | 9/77 (11.7 %) |
| 45-64y | 1/21 (4.8 %) | 12/25 (48.0 %) | 0/6 (0.0 %) | 0/4 (0.0 %) | 2/18 (11.1 %) | 15/74 (20.3 %) |
| ≥65y | 5/46 (10.9 %) | 5/17 (29.4 %) | 3/22 (13.6 %) | 2/9 (22.2 %) | 1/13 (7.7 %) | 16/107 (15.0 %) |
| Total | 17/248 (6.9 %) | 74/210 (35.2 %) | 6/71 (8.5 %) | 3/26 (11.5 %) | 22/285 (7.7 %)a | 122/840 (14.5 %)a |
| Cause of death on death registration record | Bacterial meningitis (2); Viral meningitis (1); Encephalitis (1); IMD (all others) | IMD (all fatalities) | Bacterial Meningitis (1); IMD (all others) | IMD (all fatalities) | Bacterial Meningitis (1); IMD (all others) |
The highest case fatality was observed for the MRU-confirmed cases with NHS numbers that did not link to a HES admission for meningococcal disease (NHS number+/Unlinked). Notably, the ONS death registrations recorded meningococcal disease as the cause of death for nearly all fatal cases irrespective of the linkage status among these MRU+/HESA39- cases IMD, Invasive meningococcal Disease; MRU, meningococcal reference unit; HES, Hospital Episode Statistic; NHS, National Health Service
aThe age of six MRU-confirmed cases with no NHS number was not known