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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Adv Anat Pathol. 2015 Mar;22(2):94–101. doi: 10.1097/PAP.0000000000000049

FIG. 3. Immunohistochemical assessment of mutations in ATRX and BRAF.

FIG. 3

A, Loss-of-function mutations in ATRX lead to loss of nuclear expression. H & E stained and ATRX-immunostained micrographs of ATRX-mut and ATRX-wt tumors are shown. B, positive BRAF V600E immunostaining in a mutant-harboring PXA. H& E staining also shown.