Fig. 3.

Expression of EPs in intestinal smooth muscle in rat and effects of PGE₂ and EPs agonists on the CCh-induced contraction. A showed mRNA expression of EPs in intestinal smooth muscle of rat. B: Inhibitory effect of PGE₂ on the CCh (1 µM)-induced contraction. Each symbol showed mean ± SEM (n=8 each). C: Inhibitory effects of EPs agonists on the CCh-induced contraction. Each symbol showed mean ± SEM (n=10–14). * or **P<0.05 or P<0.01, significantly different from control, respectively. 17-pt PGE₂; 17-phenyl trinor PGE₂