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. 2015 Jun 8;77(11):1443–1449. doi: 10.1292/jvms.15-0198

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©2015 The Japanese Society of Veterinary Science

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.

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Fig. 4. — Changes in CCh-induced contraction and mRNA expression of COX-2 and iNOS in the ileum isolated from wild type or peritonitis model of rat treated with LPS. LPS (15 mg/kg) was intraperitoneally injected. Each muscle strip was made 1 or 4 hr after the LPS administration. A and C showed change in CCh-induced contraction in the ileum isolated from control (open circle) or peritonitis model (closed circle) of rat. Each symbol showed mean ± SEM (n=5–9). B and D indicated changes in mRNA expression of COX-2 and iNOS in the ileum isolated from wild type or peritonitis model of rat. Each column showed mean ± SEM. * or **P<0.05 or P<0.01, significantly different from control, respectively.