Table 1.
Clinical and Demographic Data for the Derivation Cohort
| Variable | All | No AKI | AKI |
|---|---|---|---|
| n | 241 | 213 | 28 |
| Median age, yr (IQR) | 2.5 (0.8–5.9) | 2.5 (0.8–5.9) | 2.8 (1.2–7.0) |
| Males, n (%) | 150 (62) | 127 (60) | 23 (82)a |
| 28-d mortality, n (%) | 17 (9) | 8 (4) | 11 (39)a |
| Median Pediatric Risk of Mortality score (IQR) | 12 (7–21) | 12 (6–18) | 24 (19–30)b |
| Pediatric Sepsis Biomarker Risk Model mortality probability (95% CI) | 11.0 (8.9–13.3) | 8.8 (6.7–10.9) | 27.3 (18.5–36.1)c |
| Gram-negative bacteria, n (%) | 51 (21) | 43 (20) | 8 (29) |
| Gram-positive bacteria, n (%) | 57 (24) | 51 (24) | 6 (21) |
| Other pathogen isolated, n (%) | 21 (9) | 18 (8) | 3 (11) |
| No pathogen identified, n (%) | 112 (46) | 101 (47) | 11 (39) |
| Comorbidity, n (%) | 82 (34) | 71 (33) | 11 (39) |
AKI = acute kidney injury, IQR = interquartile range.
a
p < 0.05 vs no AKI cohort, chi-square test.
b
p < 0.05 vs no AKI, rank-sum test.
c
p < 0.05 vs no AKI, t test.