Table 3.
Clinical and Demographic Data for the Test Cohort
| Variable | All | No AKI | AKI |
|---|---|---|---|
| n | 200 | 180 | 20 |
| Median age, yr (IQR) | 2.6 (0.8–5.7) | 2.7 (0.8–5.7) | 2.2 (1.2–4.8) |
| Males, n (%) | 105 (53)a | 96 (53) | 9 (45) |
| 28-d mortality, n (%) | 28 (14) | 19 (11) | 9 (45)b |
| Median Pediatric Risk of Mortality score (IQR) | 13 (9–19) | 12 (9–18) | 19 (11–34)c |
| Pediatric Sepsis Biomarker Risk Model mortality probability (95% CI) | 11.6 (9.5–13.7) | 10.8 (8.7–12.9) | 18.7 (10.6–26.8)d |
| Gram-negative bacteria, n (%) | 45 (23) | 40 (22) | 5 (25) |
| Gram-positive bacteria, n (%) | 44 (22) | 38 (21) | 6 (30) |
| Other pathogen isolated, n (%) | 17 (9) | 16 (9) | 1 (5) |
| No pathogen identified, n (%) | 94 (47) | 86 (48) | 8 (40) |
| Comorbidity, n (%) | 73 (37) | 68 (38) | 5 (25) |
AKI = acute kidney injury, IQR = interquartile range.
a
p < 0.05 vs derivation cohort.
b
p < 0.05 vs no AKI cohort, chi-square test.
c
p < 0.05 vs no AKI, rank-sum test.
d
p < 0.05 vs no AKI, t test.