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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Mol Cell Cardiol. 2015 Jun 20;85:262–272. doi: 10.1016/j.yjmcc.2015.06.011

Table 3.

Steady-state and dynamic contractile parameters measured before and following incubation with OM at equivalent levels of activator [Ca2+] (pCa 6.1) in control donor human heart preparations

Group Force (mN/mm2) P1 ktr (s−1) krel (s−1) kdf (s−1)
Pre-OM 6.06±1.53 0.677±0.050 0.76±0.07 56.32±4.77 0.86±0.07
Post-OM 8.56±1.87* 0.724±0.033 0.52±0.05* 38.26±4.32* 0.49±0.03*

P1: XB stiffness; ktr: rate of force redevelopment; krel: rate of XB detachment; kdf: rate of XB recruitment. Paired t-tests were used to compare the data between pre- and post-OM treatment groups. 10 preparations were analyzed from 3 hearts, with multiple preparations from each heart. Values are expressed as mean ± S.E.M.

*

Significantly different from the corresponding pre-OM group; P < 0.05.