Table 3.
Group | Force (mN/mm2) | P1 | ktr (s−1) | krel (s−1) | kdf (s−1) |
---|---|---|---|---|---|
Pre-OM | 6.06±1.53 | 0.677±0.050 | 0.76±0.07 | 56.32±4.77 | 0.86±0.07 |
Post-OM | 8.56±1.87* | 0.724±0.033 | 0.52±0.05* | 38.26±4.32* | 0.49±0.03* |
P1: XB stiffness; ktr: rate of force redevelopment; krel: rate of XB detachment; kdf: rate of XB recruitment. Paired t-tests were used to compare the data between pre- and post-OM treatment groups. 10 preparations were analyzed from 3 hearts, with multiple preparations from each heart. Values are expressed as mean ± S.E.M.
Significantly different from the corresponding pre-OM group; P < 0.05.