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. Author manuscript; available in PMC: 2015 Dec 2.
Published in final edited form as: J Am Geriatr Soc. 2010 Sep;58(9):1749–1757. doi: 10.1111/j.1532-5415.2010.03011.x

Figure 2. Multifactorial Contribution to Blood-Brain Barrier Pathogenesis.

Figure 2

Comorbidities and medications compound BBB changes accompanying aging. Compromise of the BBB is also associated with several age-related disorders.