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. 2015 Jan 13;172(23):5531–5547. doi: 10.1111/bph.12996

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© 2014 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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(Left panel) Computed pseudo‐ECG in control and cisapride and amiodarone conditions. Both drugs prolonged QT interval. (Right panel) Comparison of simulated QT interval prolongation to experimental data for cisapride (Di Diego et al., 2003) and amiodarone (Varro et al., 1996).