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. 2015 Jan 12;172(23):5690–5703. doi: 10.1111/bph.12995

Figure 5.

figure

The protective effects of 23‐HBA on doxorubicin‐induced cytotoxicity in H9c2 cells. (A) Logarithmic plots of the inhibition curves obtained after treating the cells with doxorubicin (5 μM) in the presence or absence of 23‐HBA (0.2, 2, 20 μM). (B) Effect of 23‐HBA on caspase‐3 activity induced by doxorubicin in H9c2 cells. (C) Representative fluorescence images of Hoechst 33342 staining of H9c2 cells after different treatments. Magnification: 400×. (D) Quantification analysis of Hoechst staining. Values are expressed as mean ± SEM from six independent experiments. ***P < 0.001 versus control group without doxorubicin, # P < 0.05, ## P < 0.01, ### P < 0.001 versus control group with doxorubicin.