Table 2. Analysis of biomarkers stratified by day of fever between AKI and non-AKI (A) in all cases, (B) in leptospirosis cases, and (C) in non-leptospirosis cases.

Biomarkers	Day of fever	AKI	Non-AKI	P-value
A. In all cases (n = 206)
uNGAL, ng/mL	day 1 –day 3	179.4(4733.86)	16.1(35.94)	<0.001
	day 4 up	561.99(688.43)	21(48.02)	<0.001
pNGAL, ng/mL	day 1 –day 3	891.65(682)	102(131.5)	<0.001
	day 4 up	1300(644)	173(221.5)	<0.001
Serum creatinine,,mg/dL	day 1 –day 3	3.6(2.95)	0.96(0.32)	<0.001
	day 4 up	4.54(2.86)	0.88(0.38)	<0.001
B. In leptospirosis cases (n = 113)
uNGAL, ng/mL	day 1 –day 3	158.4(867.7)	20.8(45.7)	<0.001
	day 4 up	550.3(583.3)	23.2(64.4)	<0.001
pNGAL, ng/mL	day 1 –day 3	945(732)	111(134)	0.001
	day 4 up	1300(593.5)	211.5(147.3)	<0.001
Serum creatinine, mg/dL	day 1 –day 3	3.6(2.95)	0.98(0.32)	<0.001
	day 4 up	5.1(2.5)	0.88(0.45)	<0.001
C. In non-leptospirosis cases (n = 93)
uNGAL, ng/mL	day 1 –day 3	4793.2(7941.5)	13.3(20.6)	0.001
	day 4 up	1403.1(2355.6)	16.8(17.7)	<0.001
pNGAL, ng/mL	day 1 –day 3	725(818.8)	97.5(134.25)	0.001
	day 4 up	391(1112)	100(133.25)	0.002
Serum creatinine, mg/dL	day 1 –day 3	2.36(3.68)	0.91(0.36)	<0.001
	day 4 up	4.22(5.28)	0.88(0.28)	<0.001