Table 7. Analysis and comparison of drug resistance of 130 strains of P. aeruginosa in patients with infection.
| A(2007–2010, n = 78) | B(2011–2013, n = 52) | a P value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 2007 (n = 16) | 2008 (n = 21) | 2009 (n = 19) | 2010 (n = 22) | Total | 2011 (n = 19) | 2012 (n = 15) | 2013 (n = 18) | Total | ||
| Polymyxin B | 0 | 0 | 0 | 1 (4.17) | 1 (1.28) | 3 (15.79) | 0 | 0 | 3 (5.77) | 0.350807 |
| Ciprofloxacin | 3 (18.75) | 5 (23.81) | 2 (10.53) | 2 (9.09) | 12 (15.38) | 2 (10.52) | 2 (13.33) | 2 (11.11) | 6 (11.54) | 0.716722 |
| Cefoperazone/sulbactam | 3 (18.75) | 12 (57.14) | 3 (15.79) | 7 (31.82) | 25 (32.05) | 5 (26.31) | 4 (26.67) | 8 (44.44) | 17 (32.69) | 0.908566 |
| Meropenem | 5 (31.25) | 13 (61.90) | 5 (26.32) | 7 (31.82) | 30 (38.46) | 2 (10.52) | 4 (26.67) | 4 (22.22) | 10 (19.23) | 0.032890 |
| Ceftazidime | 4 (25.0) | 16 (76.19) | 6 (31.58) | 9 (40.91) | 35 (44.87) | 7 (36.84) | 7 (46.67) | 4 (22.22) | 18 (34.61) | 0.325281 |
| Cefoperazone | 6 (37.5) | 16 (76.19) | 5 (26.32) | 9 (40.91) | 36 (46.15) | 6 (31.58) | 6 (40) | 7 (38.89) | 19 (36.54) | 0.364974 |
| Aztreonam | 6 (37.5) | 17 (80.95) | 5 (26.32) | 12 (54.55) | 40 (51.28) | 8 (42.11) | 5 (33.33) | 6 (33.33) | 19 (36.54) | 0.140393 |
| Piperacillin/Tazobactam | 13 (81.25) | 17 (80.95) | 6 (31.58) | 7 (31.82) | 43 (55.13) | 9 (36.84) | 8 (53.33) | 5 (27.78) | 20 (38.46) | 0.092246 |
| Imipenem and Cilastatin Sodium | 7 (43.75) | 16 (76.19) | 8 (42.11) | 12 (54.55) | 43 (55.13) | 7 (36.84) | 5 (33.33) | 4 (22.22) | 16 (30.77) | 0.010677 |
| Amikacin | 14 (87.5) | 18 (85.71) | 8 (42.11) | 7 (31.82) | 47 (60.26) | 11 (57.89) | 8 (53.33) | 7 (38.89) | 26 (50) | 0.329976 |
| Cefepime | 15 (93.75) | 18 (85.71) | 9 (47.37) | 8 (36.36) | 50 (64.1) | 9 (47.37) | 9 (60) | 8 (44.44) | 26 (50) | 0.156524 |
| Ceftriaxone | 15 (93.75) | 21 (100) | 17 (89.47) | 22 (100) | 75 (96.15) | 15 (78.95) | 13 (86.67) | 16 (88.89) | 44 (84.62) | 0.046136 |
| Cefotaxime | 16 (100) | 21 (100) | 19 (100) | 22 (100) | 78 (100) | 19 (100) | 15 (100) | 18 (100) | 52 (100) | |
| Cefazolin | 16 (100) | 21 (100) | 19 (100) | 22 (100) | 78 (100) | 19 (100) | 15 (100) | 18 (100) | 52 (100) | |
| Cefuroxime | 16 (100) | 21 (100) | 19 (100) | 22 (100) | 78 (100) | 19 (100) | 15 (100) | 18 (100) | 5 (100) | |
| Ampicillin | 16 (100) | 21 (100) | 19 (100) | 22 (100) | 78 (100) | 19 (100) | 14 (93.33) | 17 (94.44) | 50 (96.13) | |
aP value for the comparison of overall drug resistance of each antibiotic before and after infection control nurses interventions.