Table 3. The significant pathways (P<0.05) from KEGG pathway analysis of DEGs.
| Pathway item | ID | Sample number | Background number | P-Value | Corrected P-Value |
|---|---|---|---|---|---|
| H-PM VS H-LM | |||||
| Focal adhesion | mmu04510 | 26 | 206 | 4.44E-16 | 5.91E-14 |
| PI3K-Akt signaling pathway | mmu04151 | 25 | 356 | 8.17E-10 | 5.43E-08 |
| ECM-receptor interaction | mmu04512 | 22 | 87 | 0 | 0 |
| Protein digestion and absorption | mmu04974 | 18 | 88 | 2.89E-15 | 2.56E-13 |
| Amoebiasis | mmu05146 | 13 | 120 | 7.07E-08 | 2.69E-06 |
| Hypertrophic cardiomyopathy (HCM) | mmu05410 | 12 | 86 | 1.28E-08 | 6.83E-07 |
| Dilated cardiomyopathy | mmu05414 | 12 | 90 | 2.17E-08 | 9.63E-07 |
| Cardiac muscle contraction | mmu04260 | 9 | 79 | 4.90E-06 | 0.000162783 |
| Tight junction | mmu04530 | 8 | 138 | 0.001771256 | 0.049590264 |
| Malaria | mmu05144 | 5 | 55 | 0.001864296 | 0.049590264 |
| P-PM VS P-LM | |||||
| Focal adhesion | mmu04510 | 21 | 206 | 4.74E-11 | 4.21E-09 |
| PI3K-Akt signaling pathway | mmu04151 | 20 | 356 | 2.85E-06 | 9.46E-05 |
| ECM-receptor interaction | mmu04512 | 16 | 87 | 1.15E-12 | 3.06E-10 |
| Protein digestion and absorption | mmu04974 | 15 | 88 | 1.86E-11 | 2.47E-09 |
| Hypertrophic cardiomyopathy (HCM) | mmu05410 | 12 | 86 | 2.09E-08 | 1.39E-06 |
| Complement and coagulation cascades | mmu04610 | 11 | 77 | 6.34E-08 | 3.37E-06 |
| Dilated cardiomyopathy | mmu05414 | 11 | 90 | 3.25E-07 | 1.44E-05 |
| Cardiac muscle contraction | mmu04260 | 10 | 79 | 8.04E-07 | 3.06E-05 |
| Amoebiasis | mmu05146 | 10 | 120 | 3.53E-05 | 0.001042685 |
| Tight junction | mmu04530 | 9 | 138 | 0.000546591 | 0.014539316 |
| Thyroid cancer | mmu05216 | 4 | 29 | 0.001325109 | 0.032043544 |
| P-LM VS H-LM | |||||
| Ribosome | mmu03010 | 10 | 161 | 1.22E-15 | 3.25E-13 |
| P-PM VS H-PM | |||||
| Complement and coagulation cascades | mmu04610 | 10 | 77 | 3.50E-12 | 9.31E-10 |
| Ribosome | mmu03010 | 6 | 161 | 0.000126348 | 0.016804306 |