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. 2015 Dec 2;10(12):e0143650. doi: 10.1371/journal.pone.0143650

Fig 3. Sox7 expression is up-regulated in Sox17-/- ECs in mosaic Sox17CKO/-;Pdgfb-CreER retinal vasculature.

Fig 3

(A-E) Flat mount retinas stained with anti-Sox7 and anti-Sox17 from Sox7 CKO/- ;Pdgfb-CreER mice at P7 (A,B), and from Sox17 CKO/- ;Pdgfb-CreER mice at P7 (C,D) and at P11 (E), following 50 μg 4HT at P2. (B,D) Scatterplots of Sox7 pixel intensity vs. Sox17 pixel intensity; (B) and (D) correspond to (A) and (C), respectively. EC nuclei in Sox17 CKO/- ;Pdgfb-CreER retinal vasculature express either Sox17 (i.e. unrecombined Sox17+ cells; lower white arrow in E) or Sox7 (recombined Sox17- cells; upper white arrow in E). Scale bar, 50 μm.