Table 3. Substrate specificity of spider venom Hyals.
Degradation (+), partial degradation (+/-) or no degradation (-) of the examined substrates (HA, CS4, DS, HS) after incubation with spider venom. The degradation process was recorded after agarose gel electrophoresis and subsequent staining with toluidine blue and Stains-All.
| Family | Species | Degraded GAGs | |||
|---|---|---|---|---|---|
| HA | CS4 | DS | HS | ||
| Mygalomorphae | |||||
| Atypidae | Atypus piceus | - | - | - | - |
| Dipluridae | Linothele megatheloides | + | +/- | - | - |
| Hexathelidae | Macrothele calpeiana | + | +/- | - | - |
| Theraphosidae | Sericopelma rubronitens | + | + | - | - |
| Araneomorphae | |||||
| Filistatidae | Filistata insidiatrix | + | + | - | - |
| Segestriidae | Segestria florentina | + | + | - | - |
| Eresidae | Eresus walckenaerius | - | - | - | - |
| Stegodyphus lineatus | - | - | - | - | |
| Oecobiidae | Uroctea durandi | + | +/- | - | - |
| Theridiidae | Latrodectus tredecimguttatus | + | + | - | - |
| Steatoda paykulliana | + | + | - | - | |
| Tetragnathidae | Meta menardi | + | +/- | - | - |
| Nephilidae | Nephila pilipes | - | - | - | - |
| Araneidae | Araneus angulatus | - | - | - | - |
| Araneus diadematus | - | - | - | - | |
| Argiope bruennichi | - | - | - | - | |
| Larinioides sclopetarius | - | - | - | - | |
| RTA-clade * | |||||
| Amaurobiidae | Callobius claustrarius | + | +/- | - | - |
| Agelenidae | Tegenaria atrica | + | + | - | - |
| Agelena labyrinthica | + | + | - | - | |
| Sparassidae | Eusparassus dufouri | + | + | - | - |
| Isopeda villosa | + | + | - | - | |
| Polybetes pythagoricus | + | + | - | - | |
| Gnaphosidae | Drassodes lapidosus | + | + | - | - |
| Zoropsidae | Zoropsis spinimana | + | + | - | - |
| Pisauridae | Dolomedes okefinokensis | + | + | - | - |
| Pisaura mirabilis | + | + | - | - | |
| Oxyopidae | Oxyopes sp. | + | + | - | - |
| Lycosidae | Alopecosa fabrilis | + | + | - | - |
| Alopecosa marikovskyi | + | + | - | - | |
| Geolycosa vultuosa | + | + | - | - | |
| Hogna radiata | + | + | - | - | |
| Lycosa hispanica | + | + | - | - | |
| Lycosa praegrandis | + | + | - | - | |
| Ctenidae | Ancylometes rufus | + | + | - | - |
| Cupiennius salei | + | + | - | - | |
| Phoneutria fera | + | + | - | - | |
| Phoneutria reidyi | + | + | - | - | |
| Viridasius fasciatus | + | + | - | - | |
*RTA-clade (araneomorph spider families exhibiting a Retrolateral Tibial Apophysis)