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. Author manuscript; available in PMC: 2016 Feb 1.
Published in final edited form as: Breast Cancer Res Treat. 2015 Jan 28;149(3):607–618. doi: 10.1007/s10549-015-3270-1

Table 1.

Combination Index Values for Trastuzumab and Imetelstat Combination Treatment

Cell Line [Imetelstat]
(μM)
[Trastuzumab]
(μM)
Combination
Index
HCC1569 0.156 0.020 0.466
0.313 0.039 0.908
0.625 0.078 0.554
1.25 0.156 0.334
2.5 0.313 0.295
5 0.625 0.313
10 1.25 1.148
20 2.5 9.013
40 5 0.327
80 10 0.060

HCC1954 0.156 0.039 0.137
0.313 0.078 0.228
0.625 0.156 0.322
1.25 0.313 0.654
2.5 0.625 1.136
5 1.25 1.343
10 2.5 1.301
20 5 0.823
40 10 0.723
80 20 0.917