Table 1.
Cell Line | [Imetelstat] (μM) |
[Trastuzumab] (μM) |
Combination Index |
---|---|---|---|
HCC1569 | 0.156 | 0.020 | 0.466 |
0.313 | 0.039 | 0.908 | |
0.625 | 0.078 | 0.554 | |
1.25 | 0.156 | 0.334 | |
2.5 | 0.313 | 0.295 | |
5 | 0.625 | 0.313 | |
10 | 1.25 | 1.148 | |
20 | 2.5 | 9.013 | |
40 | 5 | 0.327 | |
80 | 10 | 0.060 | |
| |||
HCC1954 | 0.156 | 0.039 | 0.137 |
0.313 | 0.078 | 0.228 | |
0.625 | 0.156 | 0.322 | |
1.25 | 0.313 | 0.654 | |
2.5 | 0.625 | 1.136 | |
5 | 1.25 | 1.343 | |
10 | 2.5 | 1.301 | |
20 | 5 | 0.823 | |
40 | 10 | 0.723 | |
80 | 20 | 0.917 |