Table 3. Probabilities of the closed, open, and wide-open conformations of the BC-CT for WT and mutated insulin.

Insulin	Probability
	Closed conformation	Open conformation	Wide-open conformation
WT	0.64	0.31	0.05
Y26F	0.66	0.34	0.00
Y26N	0.15	0.62	0.23
Y26G	0.07	0.05	0.88
Y26A	0.06	0.31	0.63