Table 4. Agreement and HPV positivity for each collection method, overall (n = 130) and according to cytology results (n = 119).
| Cytology analysis | N. of Samples—Self-HPV | % Positive | Agreement (%) | Kappa (95% CI) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total | s-FTA+/s-DRY+ | s-FTA+/ s-DRY- | s-FTA/ s-DRY+ | s-FTA-/ s-DRY- | s-FTA cartridge % (95% CI) | s-DRY % (95% CI) | Overall | PPA | ||
| Overall | 130 | 70 | 9 | 29 | 22 | 60.8 (52.2–68.7) | 76.2 (68.1–82.7) | 70.8 | 78.7 | 0.34 (0.18–0.50) |
| NILM | 61 (51.3) | 26 | 2 | 17 | 15 | 45.9 (34.0–58.3) | 72.1 (59.8–81.9) | 68.3 | 72.2 | 0.38 (0.18–0.59) |
| ASC-US | 20 (16.8) | 14 | 4 | 0 | 2 | 90.0 (68.7–98.4) | 70.0 (47.9–85.7) | 80.0 | 87.5 | 0.41 (-0.01–0.83) |
| AGC | 3 (2.5) | 1 | 1 | 0 | 1 | 66.7 (20.2–94.4) | 33.3 (56.3–79.8) | 66.7 | 66.7 | 0.40 (-0.37–1.0) |
| ASC-H | 9 (7.6) | 7 | 1 | 1 | 0 | 88.9 (54.3–99.9) | 88.9 (54.3–99.9) | 77.8 | 87.5 | -0.13 (-0.30–0.05) |
| LSIL | 20 (16.8) | 13 | 1 | 3 | 3 | 70.0 (47.9–85.7) | 80.0 (57.8–92.5) | 80.0 | 86.7 | 0.47 (-0.04–0.90) |
| HSIL | 5 (4.2) | 2 | 0 | 3 | 0 | 40.0 (11.6–77.1) | 100 (51.1–100) | 40.0 | 57.1 | 0 |
| CC | 1 (0.8) | 0 | 0 | 1 | 0 | 0 (0–83.3) | 100 (16.8–100) | 0 | 0 | 0 |
| LSIL+ | 26 (21.8) | 15 | 1 | 7 | 3 | 61.5 (42.5–77.6) | 84.6 (66.5–93.9) | 69.2 | 78.9 | 0.27 (-0.07–0.61) |
Abbreviations: n = number; NILM = Negative for intraepithelial lesion or malignancy; ASC-US = Atypical squamous cells of undetermined significance; ASC-H = Atypical squamous cells-cannot rule out high grade; AGC = Atypical glandular cell; LSIL = Low-grade squamous intraepithelial lesion; LSIL+ = Low-grade squamous intraepithelial lesion or worse; HSIL = High-grade squamous intraepithelial lesion; CC = Cervical Cancer; CI = confidence interval; PPA = Proportion of Positive Agreement; s-DRY = self-collected samples using dry swab without transport medium; s-FTA = self-collected samples using a cytobrush applied to an FTA cartridge.