Table 2. EEG and histological measures from aging mice in the untreated/post-CS treated or prophylactically treated cohort.

A	Post-CS treated	Prophylactic treated
Ipsilateral hippocampal EEG changes in animals with CS (% of baseline)
At end of hypoxia	28.9±4.9 (n = 8)	32.0±4.4 (n = 5)
1 hour later	38.7±9.0 (n = 8)	30.0±5.8 (n = 5)
24 hours later	18.8±4.6 (n = 2)	23.9 (n = 1)
B	Untreated	Prophylactically treated
Ipsilateral EEG changes in animals without CS and infarctions (% of baseline)
At end of hypoxia	77.2±13.0 (n = 6)	63.9±11.8 (n = 6)
1 hour later	78.8±2.6 (n = 6)	71.7±7.0 (n = 6)
24 hours later	70.8±7.9 (n = 4)	87.0±9.4 (n = 6)
C	Post-CS treated	Prophylactic treated
Ipsilateral/contralateral area ratios (%) for individual animals with ipsilateral infarctions
	85.2±0.1	51.3±2.8
	74.8±1.4	91.3±1.8
	86.7±2.3	88.2±4.4
	74.9±2.4	91.1±2.0
		66.1±2.3
		82.3±3.9
		91.2±2.7

Post-CS and prophylactic anticonvulsive treatments were conducted in two separate cohorts of aging mice (n = 24 and 21 respectively). Panel A: Changes in ipsilateral hippocampal EEG signals were analyzed in 8 and 5 animals with CS from these two cohorts respectively. Ipsilateral hippocampal EEG signals were normalized as a % of the baseline. The numbers of animals examined at different post-HI time points are indicated in the parentheses. Panel B: ipsilateral EEG signals were analyzed in untreated animals and prophylactically treated animals (n = 6 each) that did not exhibit CS and ipsilateral infarctions on later histological assessment. Data are similarly presented in Panel A. Panel C: The ratio of the ipsilateral to contralateral hemispheric areas measured in histological brain sections. These measurements were made in 4 untreated/post-CS treated animals and 7 prophylactically treated animals 4–5 weeks post-HI. There were no significant group differences in any EEG or histological measures (p>0.05, t test or Mann-Whitney Rank Sum Test).