Table 2. Adjusted* means of Digit Symbol Substitution Test score among all subjects or stratified by tertiles of serum concentrations of organochlorine pesticides.
| Hypertension (-) (n = 207) | Hypertension (+) (n = 437) | P value | Pinteraction | ||
|---|---|---|---|---|---|
| All subjects | 43.4 | 39.6 | <0.01 | ||
| Stratified analyses by tertiles of each compound (median value, interquartile ranges, unit: ng/g lipid) | |||||
| p,p’-DDT | T1 (5.7, 5.0~6.2) | 46.0 | 45.0 | 0.62 | 0.06 |
| T2 (9.4, 8.1~11.3) | 45.3 | 41.2 | 0.07 | ||
| T3 (25.6, 18.2~48.7) | 39.1 | 33.1 | <0.01 | ||
| p,p’-DDE | T1 (324.5, 216~470) | 44.1 | 44.0 | 0.97 | 0.01 |
| T2 (940.5, 751~1170) | 44.6 | 39.9 | 0.04 | ||
| T3 (2200, 1660~3240) | 42.4 | 35.0 | <0.01 | ||
| β-hexachlorocyclohexane | T1 (12.8, 9.2~16.8) | 44.7 | 42.1 | 0.22 | 0.39 |
| T2 (28.5, 23.0~35.2) | 45.2 | 41.0 | 0.05 | ||
| T3 (73.4, 53.7~114.0) | 40.5 | 36.0 | 0.05 | ||
| Trans-nonachlor | T1 (25.9, 20.7~31.5) | 45.1 | 43.0 | 0.36 | 0.14 |
| T2 (48.2, 41.7~53.4) | 45.5 | 41.4 | 0.05 | ||
| T3 (88.9, 71.7~133.0) | 40.1 | 34.4 | 0.01 | ||
| Oxychlordane | T1 (17.9, 14.3~21.1) | 45.3 | 41.5 | 0.09 | 0.62 |
| T2 (31.3, 28.1~35.2) | 45.9 | 42.6 | 0.11 | ||
| T3 (54.7, 46.0~73.9) | 39.1 | 34.8 | 0.06 | ||
| Heptachlor epoxide | T1 (5.1, 3.9~6.1) | 45.9 | 42.1 | 0.10 | 0.66 |
| T2 (10.7, 9.2~12.3) | 44.5 | 40.5 | 0.03 | ||
| T3 (23.0, 17.5~34.6) | 38.6 | 36.6 | 0.42 | ||
*Adjusted for age, sex, race-ethnicity, education, poverty income ratio, cigarette smoking, and body mass index.