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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Diabetologia. 2015 Aug 1;58(11):2647–2652. doi: 10.1007/s00125-015-3720-7

Table 2.

Correlates of hepatic and peripheral insulin sensitivity

Variable % Suppression of EGP
Rd-low
M/I-low
M/I-high
White Black White Black White Black White Black
Body composition
    Body fat (kg) 0.08 –0.64* –0.09 –0.34 0.01 –0.64* 0.12 –0.60*
    Waist 0.09 –0.65** –0.18 –0.73** –0.25 –0.67** –0.44 –0.73*
    VAT –0.04 –0.52* –0.20 –0.35 –0.34 –0.62* –0.62* –0.30
    SAT 0.19 –0.54* –0.21 –0.26 0.13 –0.45 0.17 –0.50*
Ectopic fat
    Liver fat 0.28 –0.57* –0.44 –0.41 –0.45 –0.34 –0.53 –0.21
    Soleus IMCL 0.59* –0.46 –0.16 –0.52 0.12 –0.62* –0.08 –0.46
    Soleus fat (%) 0.34 –0.56* –0.04 –0.40 0.27 –0.66* 0.09 –0.33
Muscle gene expression
    IRS –0.32 0.49 0.04 0.65* –0.15 0.56* –0.37 0.66*
    VAMP –0.37 0.43 –0.07 0.68** –0.18 0.52 –0.49 0.64*
    SCD1 –0.33 0.49 –0.03 0.90** –0.23 0.53 –0.29 0.72**
Circulating adipokines
    Adiponectin 0.41 0.49 0.47 0.77** 0.64** 0.56* 0.75** 0.71**

Values are Pearson correlation coefficients

*

p<0.05

**

p<0.01

M/I-high, M/I corrected for circulating insulin levels during the high-dose (40 mU m–2 min–1) clamp; M/I-low, M/I corrected for circulating insulin levels during the low-dose clamp; Rd-low, Rd during the low-dose (10 mU m–2 min–1 )clamp