Figure 5. Differentially expressed genes among study groups as a function of EVLP-mediated rehabilitation strategy for DCD lungs.
(A) Venn diagram showing numbers of differentially expressed genes in lungs from EVLP and EVLP+ATL1223 groups when compared to the cold static preservation (CSP) control group (FDR 1%). (B) Volcano plots depicting the gene expression profile of pairwise comparisons of indicated groups. Each dot represents a unique, differentially expressed probeset. Significant probesets [p-value ≤ 0.001 or –log10 (p-value) ≥ 3] are illustrated by red dots.