Table 1.
Comparison analysis for IL-1 signaling pathway genes between EVLP vs. CSP and EVLP+ATL1223 vs. CSP.
| Gene Symbol | Entrez Gene Name | Affymetrix identifier | Gene expression value | ||
|---|---|---|---|---|---|
| EVLP vs. CSP (probeset) | EVLP+ATL vs. CSP (probeset) | EVLP vs. CSP (fold change) | EVLP+ATL vs. CSP (fold change) | ||
| ADCY9 | adenylate cyclase 9 | -- | 1418586_at | -1.3 | |
| ECSIT | ECSIT signaling integrator | -- | 1417080_a_at | -1.2 | |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 1423100_at | 1423100_at | 2.7 | 2.8 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 1422556_at | 1422556_at | -1.6 | -1.8 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 1427510_at | 1427510_at | -1.5 | -1.5 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 1435652_a_at | 1435652_a_at | 1.2 | 1.2 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 1437225_x_at | 1437225_x_at | 1.7 | 1.9 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 1450115_at | 1450115_at | -1.3 | -1.2 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 1449159_at | 1449159_at | 1.3 | 1.3 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | 1419469_at | 1419469_at | -1.4 | -1.4 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -- | 1460649_at | -1.2 | |
| JUN | jun proto-oncogene | 1417409_at | 1417409_at | 2.0 | 2.2 |
| MAPK12 | mitogen-activated protein kinase 12 | -- | 1449283_a_at | -1.4 | |
| MAPK14 | mitogen-activated protein kinase 14 | -- | 1426104_at | 1.5 | |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 1433533_x_at | 1433533_x_at | 1.7 | 1.5 |
| TOLLIP | toll interacting protein | -- | 1423047_at | -1.2 | |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase | 1435350_at | 1435350_at | -1.3 | -1.3 |
A descriptive list of genes associated with the IL-1 signaling canonical pathway between group comparisons is shown. The number of genes down-regulated (negative fold change) in the EVLP+ALT1223 (EVLP+ATL) vs. CSP (cold static preservation) comparison is higher than the EVLP vs. CSP comparison.