Table 5.

Comparison analysis of circulating cytokines between groups at each time-point

Cytokine	L1		L2		POD1
	S vs. WS (FC)	p-value	S vs. WS (FC)	p-value	S vs. WS (FC)	p-value
IL-1β	1.3	0.373	4.6	0.003	4.2	0.002
IL-2	0.8	0.078	2.0	<0.0001	1.4	0.257
IL-4	0.9	0.354	1.6	0.008	1.6	0.023
IL-6	1.1	0.854	3.5	<0.0001	2.5	0.016
IL-8	0.6	0.157	3.1	<0.0001	2.7	0.022
IL-10	0.9	0.785	2.0	0.006	1.5	0.081
CCL20	1.3	0.418	4.0	0.030	6.8	0.005
MCP-1	0.8	0.261	2.5	0.002	5.5	0.073
TNF-α	0.9	0.608	2.3	0.001	1.8	0.004
CXCL1	0.9	0.068	1.4	0.008	1.2	0.039

FC: Fold-change