Table 3.
Clinical and biochemical characteristics of patients with liver cirrhosis according to the presence of ascites.
| Healthy controls | No ascites | Ascites | |
|---|---|---|---|
| (n) | 40 | 35 | 53 |
| Age (years) | 55 (29–56) | 51 (21–74) | 58 (24–70) |
| Esophageal varices n (%) | — | 17 (49) | 39 (74) |
| Refractory ascites n (%) | — | — | 11 (21) |
| Child-Pugh score | — | 6 (4–7) | 9 (8–10)++ |
| Creatinine (mg/dL) | 0.8 (0.7–1.0) | 0.9 (0.7–1.4) | 1.32∗∗++ (0.8–2.4) |
| Albumin (g/L) | 45 (36–57) | 34∗ (28–45) | 29∗ (16–40) |
| MAP (mmHg) | — | 88 (85–93) | 77+ (73–89) |
| Plasma renin activity (ng mL−1 h−1) | — | 0.48 (0.13–1.4) | 1.9++ (0.95–7.6) |
| Aldosterone (ng/dL) | — | 13.2 (5.5–20.9) | 33.0+++ (13.7–52.2) |
| Antidiuretic hormone (pg/mL) | — | 4.6 (2.5–5.7) | 4.5 (3.6–6.4) |
| TNF-α (pg/mL) | 25.0 (25.5–30.2) | 32.3 (31.6–45.6) | 55.0∗∗+ (37.6–64.0) |
| hs-CRP (mg/L) | 1.05 (0.58–2.5) | 3.8∗ (3.1–7.0) | 5.9∗∗ (4.9–11.0) |
| hs-TnT (ng/L) | — | 5.1 (3.0–6.6) | 10.7++ (3.0–18.5) |
| AOPPs-albumin (μmol/g) | 1.7 (0.8–2.7) | 2.2∗ (1.3–4.4) | 3.6∗+ (1.9–5.2) |
Continuous variables are expressed as median (interquartile range: IQR) and categorical variables as number (percentage). Significance between groups + P < 0.05; ++ P < 0.01, +++ P < 0.001 versus cirrhosis without ascites. AOPPs: advanced oxidation protein products; hs-TnT: high-sensitive troponin T; MAP: mean arterial pressure.