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. 2015 Dec 3;5:17515. doi: 10.1038/srep17515

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(a) A time line for the differentiation of THP-1 into macrophage-like cells. (b) Photographs of THP-1-derived macrophages after STB-HO treatment. STB-HO engulfed by macrophages is indicated by red arrow. (c) TNF-α, IL-1β and IL-12 secretion was measured in culture media of THP-1-derived macrophages. (d) Production of IL-12 from MNC-derived macrophages was detected. Treatment of LPS with IFN-γ was used to induce the polarization of macrophages. *P < .05, **P < .01, ***P < .001. Results are one representative experiment of three independent experiments. Results are shown as mean ± SD.