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. 2015 Dec 3;5:17567. doi: 10.1038/srep17567

Figure 7. Effects of surgical interventions on the expressions of regeneration-related signaling pathways.

Figure 7

(A) Protein levels of p-STAT3 (Tyr705), STAT3, Yap, nuclear and total NF-κB p65 in regenerating liver tissue at different time points post surgery were determined by western blotting. (1, sham; 2, transection; 3, LLL resection; 4, PVL; 5, ALPPS) (B) NF-κB DNA binding activity by EMSA in the regenerating liver tissues. Five micrograms of nuclear protein were used to analyze DNA binding activity by EMSA as described in Materials and Methods. (1, sham; 2, transection; 3, LLL resection; 4, PVL; 5, ALPPS) (C) Protein levels of Yap and p-STAT3 (Tyr705) in regenerating liver tissues on day 1 after different surgical interventions were determined by IHC. (***P < 0.001 compared with the other three groups).