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. 2015 Dec 3;5:17564. doi: 10.1038/srep17564

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(a) The allelic fraction of all identified somatic mutations (all sites) and non-silent sites identified by WES. The distribution of allelic fraction between all sites and non-synonymous sites differed significantly (Kolmogorov-Smirnov test, P < 2.2 × 10⁻¹⁶). For the transcribed tumor-mutated alleles, the distribution of the allelic fractions (b) and correlation (c) between mRNA and genome are shown (n = 2061). For translated tumor-mutated alleles, the distribution of the allelic fractions at the protein levels and the corresponding genome and transcriptome (n = 174) (d), and the correlation in any two of pairwise comparisons (e–g). The y-axis in a, b, and d is the probability density of allelic fraction.