Table 1. Interactional analysis with generalized linear model among ethanol, high-fat diet (HFD) and sex on neuroendocrine metabolism-related blood phenotypes in rat offspring.

Indexs	Factors
	Sex		Ethanol	HFD	Ethanol *HFD	Ethanol *Sex	HFD* Sex	Ethanol *HFD*Sex
ACTH	B	9.49	−2.51	48.98	−11.12	−10.72	−31.25	46.13
	Sig	P > 0.05	P < 0.05	P < 0.01	P < 0.01	P < 0.01	P < 0.01	P < 0.01
Corticosterone	B	37.81	−14.75	205.4	−4.21	−90.90	37.70	189.21
	Sig	P < 0.05	P > 0.05	P < 0.01	P < 0.01	P > 0.05	P < 0.01	P < 0.05
Glucose	B	0.71	1.10	2.53	−0.09	−2.02	−0.65	2.33
	Sig	P > 0.05	P < 0.01	P < 0.01	P < 0.01	P < 0.05	P > 0.05	P < 0.01
Insulin	B	1.43	−3.10	42.23	10.05	−4.23	−0.65	12.50
	Sig	P > 0.05	P < 0.05	P < 0.01	P < 0.01	P > 0.05	P > 0.05	P < 0.05
Triglyceride	B	−0.23	−0.06	−0.07	0.20	0.05	0.21	−0.15
	Sig	P < 0.05	P < 0.05	P < 0.01	P < 0.05	P > 0.05	P < 0.01	P < 0.01
TC	B	0.09	0.02	0.95	0.47	0.17	0.08	0.03
	Sig	P < 0.1	P < 0.01	P < 0.01	P < 0.01	P > 0.05	P > 0.05	P > 0.05

ACTH: adrenocorticotropic hormone; B: regression coefficient. Sig: P value, TC: total cholesterol.