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. 2015 Nov 1;9(11):ZC16–ZC18. doi: 10.7860/JCDR/2015/16384.6731

[Table/Fig-6]:

Toxic effects of Xylene on different organ systems [2,9].

Different Organ System Toxic Effects of xylene
CNS Headaches, dizziness, irritability, depression, insomnia, agitation, extreme tiredness, tremors, loss of concentration and decreased memory.
Respiratory system Irritation to nose and throat, Chest pain, shortness of breath (exposure ≥ 200 ppm), pulmonary edema (over exposure at a confined space). Because of severe lung congestion and interalveolar hemorrhage death may occur
Liver and kidney In rats, it is proved that increased exposure to xylene(>300 ppm) causes injury and fat deposition in liver and kidney.
GIT Nausea, vomiting and gastric discomfort, anorexia
Musculoskeletal system Decrease in grasping and muscle power in extremities.
Skin Skin erythaema, urticaria, vasodilation of skin, dryness and scaling of skin.
Eye Irritation to eye.
Reproductive system Crosses placental barrier and shows feto-toxic effects. Evidence of entry into breast milk. Immediate abortions.
Cancer Not much data found to cause cancer.