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. 2015 Dec 3;5:17635. doi: 10.1038/srep17635

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(a) Raw SHG image of the dermis as a function of increased skin global deformation (top to bottom). Image size: 480 × 480 μm². (b) Hair follicle segmentation revealing skin local deformation. Scale bar: 50 μm. (c) Processed SHG image (structuring element of 21 pixels) highlighting fiber orientations in every pixel with color code. Image size: 480 × 480 μm². (d) Orientation histograms showing collagen increasing alignment along the traction direction.