Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 3;5:17642. doi: 10.1038/srep17642

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

C57BL/6 mice were i.p. injected with KLH (100 μg/mouse) or OVA (100 μg/mouse). The immunized mice were i.p. injected once with Alum (33.0 mg/kg mouse), Az (2.25 mg/kg mouse) or PolyI:C (6.65 mg/kg mouse). Boost immunization was performed by using the same protocol as prime immunization at 3 weeks after prime immunization. Sera were collected at the indicated times. Production of total IgG, IgG1 and IgG2c antibodies specific to (a) KLH or (b) OVA was determined by using an ELISA (●; No adjuvant, ; Alum, ; Az, ; PolyI:C). Graphs show mean ± s.e.m. Data shown in (a,b) are representative of three independent experiments (n = 3–5 mice per group in each experiment). ^*p < 0.05; ^**p < 0.01; ^***p < 0.001.

Inline graphic — C57BL/6 mice were i.p. injected with KLH (100 μg/mouse) or OVA (100 μg/mouse). The immunized mice were i.p. injected once with Alum (33.0 mg/kg mouse), Az (2.25 mg/kg mouse) or PolyI:C (6.65 mg/kg mouse). Boost immunization was performed by using the same protocol as prime immunization at 3 weeks after prime immunization. Sera were collected at the indicated times. Production of total IgG, IgG1 and IgG2c antibodies specific to (a) KLH or (b) OVA was determined by using an ELISA (●; No adjuvant, ; Alum, ; Az, ; PolyI:C). Graphs show mean ± s.e.m. Data shown in (a,b) are representative of three independent experiments (n = 3–5 mice per group in each experiment). ^*p < 0.05; ^**p < 0.01; ^***p < 0.001.