Table 2.
Comparison between the average SCQ scores for each clinical and genetic feature
| Gender | Male | Female | ||
| Number of patients | 18 (42.8 %) | 24 (57.1 %) | NS | |
| Average SCQ score ±SD | 10.6 ± 7.0 | 11.2 ± 8.5 | ||
| Mutation | TSC1 | TSC2 | NMI | |
| Number of patients | 10 (23.8 %) | 30 (71.4 %) | 2 (4.8 %) | |
| Average SCQ score ±SD | 6.3 ± 6.0 | 12.6 ± 8.0 | 9.5 ± 3.5 | NS p<0.03* |
| 6.3 ± 6.0 | 12.6 ± 8.0 | |||
| Epilepsy | Present | Absent | ||
| Number of patients | 36 (85.7 %) | 6 (14.3 %) | ||
| Average SCQ score ±SD | 12.1 ±7.7 | 4.2 ± 4.7 | p<0.05* | |
| Onset of seizures | Before age 12 months | After age 12 months | ||
| Number of patients | 25 (69.4 %) | 11 (30.6 %) | ||
| Average SCQ score ±SD | 14.0 ± 7.4 | 7.5 ± 6.4 | p<0.05* | |
| Spasms | Present | Absent | ||
| Number of patients | 18 (50 %) | 18 (50 %) | ||
| Average SCQ score ±SD | 15.1 ±7.4 | 8.2 ± 6.6 | p<0.05* | |
| AEDs (at time of evaluation) | Monotherapy | Polytherapy | ||
| Number of patients | 13 (39.4 %) | 20 (60.6 %) | ||
| Average SCQ score ±SD | 10.1 ± 9.0 | 13.6 ± 6.3 | NS | |
| Seizure frequency | None | Monthly | Weekly | |
| Number of patients | 19 (52.8 %) | 7 (19.4 %) | 10 (27.8 %) | |
| Average SCQ score ±SD | 9.9 ± 8.0 | 15.7 ± 5.3 | 13.6 ± 7.8 | NS |
| IQ | IQ≥70 | IQ<70 | ||
| Number of patients | 11 (36.7 %) | 19 (63.3 %) | ||
| Average SCQ score ±SD | 4.8 ± 4.3 | 11.5 ±6.7 | p<0.05* | |
| Sleep disorders | Present | Absent | ||
| Number of patients | 9 (21.4 %) | 33 (78.6 %) | ||
| Average SCQ score ±SD | 16.4 ± 8.0 | 9.4 ± 7.1 | p<0.05* | |
| Psychiatric disorders | Present | Absent | ||
| Number of patients | 17 (41.5 %) | 24 (58.5 %) | ||
| Average SCQ score ±SD | 13.3 ± 8.7 | 8.6 ± 6.0 | p<0.05* | |
Statistically significant findings are written in bold
NS not statistically significant; AEDs antiepileptic drugs