Table 1.
Demographic data and single-photon emission computed tomography observation of patients with cobalamin deficiency
| Patient # | Age/Gender | Education level (years) | Serum cobalamin level (pg/ml) | Clinical Dementia Rating | Mini-Mental State Examination | Cognitive Abilities Screening Instrument | Single-photon emission computed tomography | Clinical presentations |
|---|---|---|---|---|---|---|---|---|
| 1 | 73/F | 0 | 199 | 1 | 12 | 34 | Bil. F. T. P. Tha. (more severe in Lt) Lt BG. | Forgetfulness, attention deficits, dysexcutive syndrome, and dementia |
| 2 | 80/F | 0 | 230 | 1 | 13 | 42 | Bil. F. T. Tha. Rt BG | Forgetfulness and dementia |
| 3 | 60/F | 6 | 207 | 0.5 | 24 | 78 | Bil. F. T. Tha. | Insomnia, forgetfulness, attention deficits, and dysexcutive syndrome |
| 4 | 81/M | 12 | 177 | 0.5 | 25 | 82 | Bil. F. T. Tha.BG (more severe in Rt) | Depression, forgetfulness, attention deficits, and dysexcutive syndrome |
| 5 | 53/F | 6 | 218 | 0.5 | 22 | 65 | Bil. F. T. Tha. | Dysexecutive syndrome, anxiety, and insomnia |
| 6 | 74/F | 6 | 209 | 0.5 | 21 | 61 | Bil. F. T. Tha. | Forgetfulness, attention deficits, dysexcutive syndrome, and anxiety |
| 7 | 58/F | 12 | 210 | 0 | 28 | 88 | Bil. F. T. Tha. | Anxiety, insomnia, and dysexcutive syndrome |
| 8 | 56/F | 12 | 229 | 0.5 | 27 | 87 | Bil. T. Tha. | Dysexecutive syndrome |
| 9 | 65/F | 6 | 202 | 0.5 | 26 | 93 | Bil. T. Rt Tha. | Attention deficits |
| 10 | 61/M | 6 | 108 | 0.5 | 27 | 75 | Bil. T. (more severe in Lt) Lt BG |
Irritability, forgetfulness, and dysexcutive syndrome |
| 11 | 29/F | 12 | 199 | 0 | N.A. | N.A. | Lt T. Tha. | Irritability, anxiety, dysthymia, and sleep disorders |
| 12 | 41/M | 12 | 175 | 0 | N.A. | N.A | Bil. T. Rt BG | Anxiety |
Abbreviations: F Famale, M: Male, N.A non-available, Bil bilateral, Rt right, Lt left, F frontal region, T temporal region, P parietal region, Tha thalamus, BG basal ganglia