TABLE 3.
Characteristics | Unadjusted | Adjusted | ||||
---|---|---|---|---|---|---|
|
|
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OR | 95% CI | pa | OR | 95% CI | pb | |
Male sex | 0.97 | 0.76–1.22 | 0.77 | |||
| ||||||
Race | ||||||
Caucasian | Ref | Ref | ||||
African American | 0.92 | 0.67–1.26 | 0.06 | 0.92 | 0.67–1.28 | 0.06 |
Asian | 1.43 | 0.90–2.25 | 1.26 | 0.77–2.05 | ||
Hispanic | 1.40 | 0.98–2.01 | 1.40 | 0.96–2.04 | ||
Other | 1.64 | 0.97–2.76 | 1.85 | 1.08–3.17 | ||
| ||||||
Age group | ||||||
Neonate (0–28 d) | Ref | 0.003 | Ref | 0.002 | ||
Infant (29–365 d) | 1.02 | 0.74–1.40 | 1.04 | 0.74–1.45 | ||
Child (366 d to 18 yr) | 1.53 | 1.16–2.00 | 1.66 | 1.22–2.25 | ||
| ||||||
Cardiac diagnosis | ||||||
CHD | 0.99 | 0.78–1.26 | 0.95 | |||
Non-CHD | Ref | |||||
| ||||||
Genetic anomaly | 1.42 | 0.64–3.10 | 0.38 | |||
| ||||||
Pre-ECMO | ||||||
Pre-ECMO support | ||||||
Pressor support | 1.10 | 0.79–1.54 | 0.57 | |||
Cardiac mechanical support | 1.65 | 0.60–4.52 | 0.31 | |||
Pulmonary vasodilatory support | 1.02 | 0.75–1.37 | 0.91 | |||
Systemic afterload reduction | 1.17 | 0.91–1.52 | 0.22 | |||
Steroids | 0.82 | 0.35–1.79 | 0.62 | |||
Bicarbonate | 1.10 | 0.83–1.45 | 0.50 | |||
Pre-ECMO re-exploration for bleeding/mediastinal exploration | 20.8 | 4.21 to infinity | 0.0002 | |||
| ||||||
On ECMO | ||||||
Duration of ECMO, hr | < 0.0001 | < 0.0001 | ||||
< 128 (< 50th percentile) | Ref | Ref | ||||
128–219 (50th to 75th percentile) | 1.29 | 0.96–1.72 | 1.37 | 1.01–1.86 | ||
≥219 (> 75th percentile) | 1.88 | 1.41–2.50 | 2.05 | 1.52–2.77 | ||
ECMO mode | 0.22 | |||||
Venoarterial | 2.00 | 0.70–7.14 | ||||
Venovenous or other | Ref | |||||
Cannulation site | 0.01 | 0.0005 | ||||
Chest | 1.44 | 1.10–1.88 | 1.75 | 1.32–2.33 | ||
Neck | Ref | Ref | ||||
Groin or other | 1.57 | 1.03–2.40 | 1.28 | 0.81–2.03 |
OR = odds ratio, Ref = reference category, CHD = congenital heart disease, ECMO = extracorporeal membrane oxygenation.
p value from univariate logistic regression.
p value from multivariable logistic regression.