Table 1.

Classification of colon cancer subtypes based on genetic and epigenetic alterations (according to [3, 4])

	Type 1	Type 2	Type 3	Type 4	Type 5 (Lynch syndrome)
MSI status	MSI-H	MSS/MSI-L	MSS/MSI-L	MSS/MSI-L	MSI-H
CIMP	+	+	-	-	-
Mutations
BRAF	mutant	mutant	wild-type	wild-type	wild-type
KRAS	wild-type	wild-type	mutant	wild-type	wild-type
5-year survival
n	100	55	353	631	50
Overall	80.5%	46.2%	67.8%	78.0%	84.1%
Disease-specific	89.5%	49.2%	72.4%	82.5%	93.1%