Table 1.
Baseline blood test results (minimum and maximum values) for study horses obtained at the beginning of Phases 1 and 2
| Phase 1 | Phase 2 | ||||
|---|---|---|---|---|---|
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| Parameter | Minimum | Maximum | Minimum | Maximum | Reference interval |
| Red blood cell count (×1012/L) | 6.3 | 8.5 | 6.6 | 9.5 | 7.0 to 12.0 |
| Hemoglobin (g/L) | 116 | 141 | 120 | 154 | 110 to 170 |
| Hematocrit (%) | 33 | 40 | 35 | 45 | 30 to 44 |
| Platelets (×109/L) | 102 | 158 | 97 (clumping) | 456 | 100 to 400 |
| White blood cell count (×109/L) | 4.1 | 8.4 | 5.5 | 11.1 | 5.5 to 12.5 |
| Neutrophils (×109/L) | 2.05 | 5.54 | 3.08 | 6.33 | 2.6 to 7.5 |
| Fibrinogen (g/L) | 1.71 | 3.45 | 1.87 | 3.56 | 0.76 to 2.3 |
| Total protein (g/L) | 61 | 68 | 60 | 75 | 56 to 80 |
| AST (U/L) | 234 | 621 | 447 | 1245 | 180 to 350 |
| LDH (U/L) | 224 | 530 | 228 | 592 | 150 to 450 |
| GGT (U/L) | 11 | 16 | 26 | 86 | 1 to 35 |
| Total bilirubin (μmol/L) | 17.9 | 35.8 | 12.3 | 23.6 | 13.7 to 54.7 |
| BUN (mmol/L) | 3.5 | 6.4 | 3.7 | 6.8 | 2.86 to 9.28 |
| Creatinine (μmol/L) | 90 | 130 | 77 | 94 | 88 to 194 |
| Creatine kinase (U/L) | 215 | 583 | 180 | 519 | 100 to 300 |
AST — aspartate aminotransferase; LDH — lactic dehydrogenase; GGT — gamma-glutamyl transferase; BUN — blood urea nitrogen.