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. 2015 Aug 20;2(3):177–185. doi: 10.1093/rb/rbv009

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© The Author(s) 2015. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 10. — Representative photomicrographs (200×, scale bar = 100 μm) of injection sites immunohistochemically stained with ED1, an antibody against the monocyte/macrophage marker CD68. Tissues were harvested on (A) Day 3, (B) Day 14 and (C) Day 28 post-injection. (D) The number of ED1-positive cells decreased with time, indicating a reduction in the inflammatory response. Images from 5 random areas around the injection sites were used for quantification at each time point. Data are shown as mean ± SD (n > 5). **P < 0.001.