Table 1.
Dichotomous and continuous variables between AAA patients and controls and their associations with plasma medians of IL6, IFN-γ, IL10, IL17A, and CRP levels.
Dichotomous variables | AAA vs. Non-AAAa (OR [95% CI]) | IL6 (25. 50. and 75 Percentiles) (No vs. Yes)b | IFN-γ (25. 50. and 75 Percentiles ) (No vs. Yes)b | IL10 (25. 50. and 75 Percentiles ) (No vs. Yes)b | IL17A (25. 50. and 75 Percentiles ) (No vs. Yes)b | CRP 25. 50. and 75 Percentiles) (No vs. Yes)b |
---|---|---|---|---|---|---|
Current smoking | 3.44 [2.31; 5.13]*** | 0.00; 1.35; 4.277 0.00; 1.42; 3.49* |
6.35; 6.88; 46.8 5.52; 13.96; 40.32 |
0.00; 11.0; 62.0 0.00; 0.00; 0.00 |
0.00; 0.00; 0.00 0.00; 0.00; 10.1 |
1.1; 2.3; 4.9 1.7; 3.8; 7.7*** |
Diabetes Mellitus | 0.70 [0.44; 1.11] | 0.00; 1.42; 4.52 0.00; 1.03; 3.37 |
6.22; 17.1; 47.1 5.92; 14.6; 44.6 |
0.00; 10.7; 69.7 0.04; 14.0; 104.8 |
0.00; 0.00; 11.1 0.00; 0.00; 10.5 |
1.4; 2.7;5.6 0.9; 2.6; 6.1 |
Hypertension | 1.52 [1.10; 2.10]*** | 0.00; 1.32; 3.75 0.00; 1.40; 4.88 |
6.44; 17.2; 43.2 6.22; 16.1; 56.6 |
0.00; 12.1; 86.0 6.22; 16.17; 56.6 |
0.00; 0.00; 11.1 0.00; 0.00; 10.46 |
1.4; 2.6; 5.2 1.4;2.7;6.2 |
Use of ACE-inhibitor | 1.35 [0.92; 1.98] | 0.00; 1.15; 4.26 0.00; 1.64; 4.83 |
5.99; 17.4; 46.8 6.61; 15.0; 55.2 |
0.00; 10.9; 84.60 0.00; 9.16; 60.8 |
0.00; 0.00; 13.9 0.00; 0.00; 8.90 |
1.4; 2.6;5.3 1.3; 2.7; 6.5 |
Use of β-blocker | 1.49 [1.02; 2.17]** | 0.00; 1.10; 3.75 0.00; 1.85; 5.86* |
5.87; 16.4; 44.2 7.10; 19.2; 62.0 |
0.00; 10.7; 71.8 0.00; 11.6; 74.7 |
0.00; 0.00; 9.95 0.00; 0.00; 10.5 |
1.4; 2.6; 5.5 1.3; 2.7; 6.0 |
Use of statin | 2.15 [1.54; 2.99]*** | 0.00; 1.19; 3.96 0.00; 1.47; 4.86 |
6.80; 18.2; 51.6 5.45; 15.0; 42.0* |
0.00; 11.0; 87.8 5.45; 15.0; 42.1 |
0.00; 0.00; 13.9 0.00; 0.00; 9.83 |
1.5; 2.9; 6.5 1.1;2.4; 5.0*** |
Use of steroids | 1.53 [0.78; 3.03] | 0.00; 1.23; 4.58 0.00; 1.58; 4.01 |
6.00; 15.9; 47.1 7.34; 21.2; 44.6 |
0.00; 11.5; 76.2 0.00; 8.18; 44.1 |
.0.00; 0.00; 10.4 0.00; 0.00; 14.0 |
1.3; 2.4; 5.3 2.1; 5.1; 8.6*** |
Use of NSAIDs | 9.07 [1.22; 67.50]*** | 0.00; 1.33; 4.60 0.00; 1.02; 2.28 |
6.08; 17.1; 48.4 4.07; 10.3; 25.5 |
0.00; 17.8; 76.2 0.00; 8.47; 46.0 |
0.00; 0.00; 9.78 0.00; 2.63; 27.7 |
1.3; 2.6; 5.6 1.0; 2.6; 9.3 |
Continuous variables |
25. 50. and 75 Percentiles Non-AAA vs. AAAb |
IL6 (Rho)c | IFN-γ (Rho)c | IL10 (Rho)c | IL17A (Rho)c | CRP (Rho)c |
Systolic blood pressure (mmHg) | 137; 146; 159 142; 155; 169*** |
-0.025 | -0.042 | -0.103*** | -0.073 | -0.006 |
Diastolic blood pressure (mmHg) | 74; 80; 87 79; 87; 95*** |
-0.001 | -0.037 | -0.067* | -0.017 | 0.098** |
Age (Years) | 67.2; 69.3; 71.9 67.6; 69.9; 72.4** |
0.011 | -0.033 | -0.048 | -0.036 | -0.024 |
Body mass index | 24.4; 25.9; 27.6 24.9; 27.2; 29.4*** |
-0.018 | -0.012 | -0.012 | 0.001 | 0.137*** |
Chi-square test;
Mann-Whitney U test;
Spearman's correlation test.
P<0.10 (considered as confounding factor);
P<0.05;
P<0.01