Table 6. Univariable and Multivariable-Adjusted Regression Analyses of Correlation between Normalized Regional GMV and TMT.
Abbreviations: GMV, gray matter volume; TMT, Trail Making Test.
| TMT-A | TMT-B | ΔTMT | ||
|---|---|---|---|---|
| Normalized Frontal GMV | ||||
| Univariable analysis | Standardized β | - 0.436 | - 0.468 | - 0.436 |
| P | <0.001 | <0.001 | <0.001 | |
| Multivariable analysis * | Standardized β | - 0.279 | - 0.287 | - 0.263 |
| P | 0.03 | 0.02 | 0.03 | |
| Normalized Temporal GMV | ||||
| Univariable analysis | Standardized β | - 0.498 | - 0.498 | - 0.527 |
| P | <0.001 | <0.001 | <0.001 | |
| Multivariable analysis * | Standardized β | - 0.352 | - 0.396 | - 0.375 |
| P | 0.005 | <0.001 | 0.002 | |
| Normalized Parietal GMV | ||||
| Univariable analysis | Standardized β | - 0.283 | - 0.333 | - 0.320 |
| P | 0.005 | 0.001 | 0.002 | |
| Multivariable analysis * | Standardized β | - 0.105 | - 0.141 | - 0.141 |
| P | 0.4 | 0.2 | 0.2 | |
| Normalized Occipital GMV | ||||
| Univariable analysis | Standardized β | - 0.137 | - 0.164 | - 0.159 |
| P | 0.2 | 0.1 | 0.1 | |
| Multivariable analysis * | Standardized β | 0.003 | - 0.009 | 0.060 |
| P | 0.9 | 0.9 | 0.6 | |
* Multivariable adjustment was performed for age, gender, diabetes mellitus, systolic blood pressure, smoking habits, drinking habits, education, hemoglobin, estimated glomerular filtration rate, and log-transformed urinary protein to creatinine ratio.