Table 1. Patients’ characteristics.
| CTZ Group n = 88(%) | CT Group n = 92(%) | p-value* | |
|---|---|---|---|
| Age at randomization | |||
| mean | 49.5 | 49 | 0.912 |
| range | 34–71 | 28–70 | |
| Menopausal status | |||
| Premenopausal | 50(56.8) | 53(57.6) | 1.000 |
| Postmenopausal | 38(43.2) | 39(42.4) | |
| T-stage | |||
| cT1 | 2(2.3) | 1(1.1) | 0.784 |
| cT2 | 66(75.0) | 73(79.3) | |
| cT3 | 13(14.8) | 13(14.1) | |
| cT4 | 7(8.0) | 5(5.4) | |
| N-stage | |||
| pN+ | 30(34.1) | 34(37.0) | 0.756 |
| pN- | 58(65.9) | 58(63.0) | |
| ER status | |||
| ER+ | 71(80.7) | 75(81.5) | 1.000 |
| ER- | 17(19.3) | 17(18.5) | |
| PgR status | |||
| PgR+ | 66(75.0) | 69(75.0) | 1.000 |
| PgR- | 22(25.0) | 23(25.0) | |
| Histology | |||
| Invasive ductal carcinoma | 85(96.6) | 88(95.7) | 1.000 |
| Invasive lobular carcinoma | 1(1.1) | 2(2.2) | |
| Others | 2(2.3) | 2(2.2) | |
| Planned surgery | |||
| Lumpectomy | 38(43.2) | 41(44.6) | 0.881 |
| Mastectomy | 50(56.8) | 51(55.4) |
*Mann–Whitney U test and Fisher’s exact test (two-sided).
CTZ = chemotherapy + zoledronic acid; CT = chemotherapy alone; pN = pathological node-positive or -negative; ER = estrogen receptor; PgR = progesterone receptor.