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. 2015 Dec 3;10(12):e0143643. doi: 10.1371/journal.pone.0143643

Table 2. Pathological complete response.

TOTAL CTZ group(%)95%CI CT group(%) 95%CI Pvalue*
All patients 179 13/88(14.8) 7.4–22.2 7/91(7.7) 2.2–13.2 0.066
Pre menopausal 102 6/50(12.0) 3.0–21.0 5/52(9.6) 1.6–17.6 0.349
Post menopausal 77 7/38(18.4) 6.1–30.7 2/39(5.1) 0.0–12.0 0.071**
Luminal 145 7/71(9.9) 3.0–16.8 5/74(6.8) 1.1–12.5 0.249
Triple negative (TN) 34 6/17(35.3) 12.6–58.0 2/17(11.8) 0.0–27.1 0.112**
Pre menopausal & TN 17 2/9 (22.2) 0.0–49.1 2/8(25.0) 0.0–55.0 0.665**
Post menopausal & TN 17 4/8(50.0) 15.4–84.6 0/9 (0.0) 0.029**

† 95 percent confidence interval.

*P value based on one-sided chi-squared test.

**P value based on Fisher’s exact test.

CTZ = chemotherapy + zoledronic acid; CT = chemotherapy alone.