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. 2015 Dec 3;10(12):e0143800. doi: 10.1371/journal.pone.0143800

Table 3. Age- and sex-specific observed incidence rates of major osteoporotic fracture as compared to those predicted by the imputation method.

Hip observed MOF observed MOF predicted *
N IR N IR N IR SIR (95% CI)
Women
    50–54 35 2.1 363 22.2 383 23.4 0.95 (0.85–1.05)
    55–59 47 3.0 552 35.6 481 31.0 1.15 (1.05–1.25)
    60–64 94 6.7 717 52.2 507 36.9 1.41 (1.31–1.52)
    65–69 103 9.3 682 63.2 454 42.1 1.50 (1.39–1.62)
    70–74 178 19.3 763 85.3 625 69.9 1.22 (1.14–1.31)
    75–79 254 35.6 795 115.8 586 85.4 1.36 (1.26–1.45)
    80–84 330 72.3 729 167.4 598 137.3 1.22 (1.13–1.31)
    85–89 263 116.5 477 223.6 460 215.6 1.04 (0.95–1.13)
    90+ 199 229.1 295 361.4 335 410.1 0.88 (0.78–0.99)
Men
    50–54 36 2.1 261 15.0 160 9.2 1.63 (1.44–1.84)
    55–59 66 3.8 307 18.0 280 16.4 1.10 (0.98–1.23)
    60–64 63 4.0 305 19.7 338 21.9 0.90 (0.80–1.01)
    65–69 51 4.3 216 18.5 177 15.1 1.22 (1.06–1.39)
    70–74 95 10.6 246 27.7 243 27.4 1.01 (0.89–1.15)
    75–79 112 18.5 240 40.1 230 38.4 1.05 (0.92–1.19)
    80–84 121 38.9 204 66.4 198 64.6 1.03 (0.89–1.18)
    85–89 82 71.7 129 114.7 163 144.8 0.79 (0.66–0.94)
    90+ 37 117.7 51 166.7 62 203.6 0.82 (0.61–1.08)

Abbreviations: IR; incidence rate, 95% CI; 95% Confidence Interval, MOF; major osteoporotic fracture (first fracture of the hip, clinical spine, humerus, or forearm, according to the FRAX® definition), SIR; standardized incidence ratio

*Predicted MOF rates were calculated by multiplying observed hip fracture rates by the age-and-sex-specific Swedish incidence rate ratios for first hip fracture to a first MOF. The expected number of MOF fractures were calculated by multiplying the predicted MOF rate to the total number of person-years in the corresponding age-and-sex-specific group.