Table 3. Age- and sex-specific observed incidence rates of major osteoporotic fracture as compared to those predicted by the imputation method.
Hip observed | MOF observed | MOF predicted * | |||||
---|---|---|---|---|---|---|---|
N | IR | N | IR | N | IR | SIR (95% CI) | |
Women | |||||||
50–54 | 35 | 2.1 | 363 | 22.2 | 383 | 23.4 | 0.95 (0.85–1.05) |
55–59 | 47 | 3.0 | 552 | 35.6 | 481 | 31.0 | 1.15 (1.05–1.25) |
60–64 | 94 | 6.7 | 717 | 52.2 | 507 | 36.9 | 1.41 (1.31–1.52) |
65–69 | 103 | 9.3 | 682 | 63.2 | 454 | 42.1 | 1.50 (1.39–1.62) |
70–74 | 178 | 19.3 | 763 | 85.3 | 625 | 69.9 | 1.22 (1.14–1.31) |
75–79 | 254 | 35.6 | 795 | 115.8 | 586 | 85.4 | 1.36 (1.26–1.45) |
80–84 | 330 | 72.3 | 729 | 167.4 | 598 | 137.3 | 1.22 (1.13–1.31) |
85–89 | 263 | 116.5 | 477 | 223.6 | 460 | 215.6 | 1.04 (0.95–1.13) |
90+ | 199 | 229.1 | 295 | 361.4 | 335 | 410.1 | 0.88 (0.78–0.99) |
Men | |||||||
50–54 | 36 | 2.1 | 261 | 15.0 | 160 | 9.2 | 1.63 (1.44–1.84) |
55–59 | 66 | 3.8 | 307 | 18.0 | 280 | 16.4 | 1.10 (0.98–1.23) |
60–64 | 63 | 4.0 | 305 | 19.7 | 338 | 21.9 | 0.90 (0.80–1.01) |
65–69 | 51 | 4.3 | 216 | 18.5 | 177 | 15.1 | 1.22 (1.06–1.39) |
70–74 | 95 | 10.6 | 246 | 27.7 | 243 | 27.4 | 1.01 (0.89–1.15) |
75–79 | 112 | 18.5 | 240 | 40.1 | 230 | 38.4 | 1.05 (0.92–1.19) |
80–84 | 121 | 38.9 | 204 | 66.4 | 198 | 64.6 | 1.03 (0.89–1.18) |
85–89 | 82 | 71.7 | 129 | 114.7 | 163 | 144.8 | 0.79 (0.66–0.94) |
90+ | 37 | 117.7 | 51 | 166.7 | 62 | 203.6 | 0.82 (0.61–1.08) |
Abbreviations: IR; incidence rate, 95% CI; 95% Confidence Interval, MOF; major osteoporotic fracture (first fracture of the hip, clinical spine, humerus, or forearm, according to the FRAX® definition), SIR; standardized incidence ratio
*Predicted MOF rates were calculated by multiplying observed hip fracture rates by the age-and-sex-specific Swedish incidence rate ratios for first hip fracture to a first MOF. The expected number of MOF fractures were calculated by multiplying the predicted MOF rate to the total number of person-years in the corresponding age-and-sex-specific group.