Table 1. Clinicopathologic characteristics of the patients.
| Parameter | Training cohort (n=65), n [%] | Validation cohort (n=32), n [%] | P |
|---|---|---|---|
| Median age, y | 61 | 56 | 0.051 |
| Range | 21-71 | 33-75 | |
| Sex | 0.66 | ||
| Male | 55 [85] | 28 [87] | |
| Female | 10 [15] | 4 [13] | |
| Histologic subtype | 0.37 | ||
| Epitheliod | 48 [74] | 23 [72] | |
| Sarcomatoid | 3 [5] | 1 [3] | |
| Biphasic | 12 [18] | 8 [25] | |
| Others | 2 [3] | 0 | |
| Pathological IMIG stage | 0.038 | ||
| I-II | 6 [9] | 8 [25] | |
| III-IV | 58 [89] | 24 [75] | |
| Unknown | 1 [2] | 0 | |
| Treatment | 0.0001 | ||
| CT + EPP + RT | 34 [52] | 3 [9] | |
| CT + EPP | 12 [19] | 23 [72] | |
| RT + EPP | 11 [17] | 0 | |
| EPP + RT | 6 [9] | 0 | |
| EPP + CT | 0 | 3 [9] | |
| EPP | 2 [3] | 3 [9] | |
| Completeness of resection | 0.13 | ||
| MCR | 61 [94] | 27 [84] | |
| MIR | 4 [6] | 5 [16] | |
IMIG, International Mesothelioma Interest Group; CT, chemotherapy; EPP, extrapleural pneumonectomy; RT, radiotherapy; MCR, macroscopic complete resection; MIR, macroscopic incomplete resection.